IL-21R-STAT3 SIGNALLING INITIATES A DIFFERENTIATION PROGRAM IN UTERINE TISSUE-RESIDENT NK CELLS TO SUPPORT PREGNANCY

IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy

Abstract Tissue-resident Natural Killer (trNK) cells are crucial components of local immunity that activate rapidly upon infection.However, under steady state conditions, their responses are tightly controlled to prevent unwanted tissue damage.The mechanisms governing their differentiation and activation are not fully understood.Here, we characteri

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Back pain: diagnostic and differential aspects

Management of patients with back pain is an interdisciplinary problem requiring a package of diagnostic and differential measures.Despite the elaboration of algorithms for the differential diagnosis and therapy of back pain, a number of questions Enamel Flower Tea Cup remain difficult to interpret, which can lead to diagnostic errors.This review co

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Far-field ultrasonic imaging using hyperlenses

Abstract Hyperlenses for ultrasonic imaging in nondestructive evaluation and non-invasive diagnostics have not been Dining Stool widely discussed, likely due to the lack of understanding on their performance, as well as challenges with reception of the elastic wavefield past fine features.This paper discusses the development and application of a cy

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The relevance of specific heart failure outpatient programs in the COVID era: an appropriate model for every disease

Heart Failure (HF) is characterized by an elevated readmission rate, with almost 50% of events occurring after the first episode over the first 6 months of the post-discharge period.In this context, the vulnerable phase represents the period when patients elapse from a sub-acute to a more stabilized chronic phase.The lack of an accurate approach fo

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